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KMID : 0360220150560010039
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Journal of the Korean Ophthalmological Society
2015 Volume.56 No. 1 p.39 ~ p.46
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Short-Term Outcome of Intravitreal Dexamethasone Implant for Macular Edema Secondary to Branch Retinal Vein Occlusion
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Kang Sun-Ah
Kim Jong-Woo
Kim Chul-Gu
Lee Tae-Gon
Kim Jae-Hui
Lew Young-Ju
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Abstract
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Purpose: To evaluate short-term outcomes of intavitreal dexamethasone implant in macular edema secondary to branch retinal vein occlusion (BRVO).
Methods: A retrospective review of medical records was performed for 24 patients (24 eyes) who were diagnosed with macular edema secondary to BRVO. The best-corrected visual acuity (BCVA) and central foveal thickness (CFT) were measured before the injection and at 1 and 3 months after the injection. The values measured before and after the treatment were compared. In addition, the association between duration of symptoms and 3-month changes in BCVA was evaluated.
Results: In 24 eyes, the logarithm of minimal angle of resolution BCVA before the injection and 1 and 3 months after the injection was 0.56 ± 0.25, 0.42 ± 0.26 and 0.45 ± 0.27, respectively. The CFT was 550.2 ± 116.5 μm, 270.3 ± 101.5 μm, and 356.6 ± 173.7 μm, respectively. When compared with the baseline values, the BCVA at 3 months was significantly improved (p = 0.018) and the CFT was significantly decreased (p < 0.001). There was a significant negative association between the duration of symptoms and 3-month changes in BCVA (p = 0.032, r = -0.375). Elevated intraocular pressure was observed in 3 eyes (12.5%).
Conclusions: Intravitreal dexamethasone implant was found effective in treating macular edema secondary to BRVO. However, rebound macular edema and deterioration in visual acuity after 1 month suggest further studies with longer follow-ups are necessary.
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KEYWORD
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inical outcome, Dexamethasone, Ozurdex, Retinal vein occlusion
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